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Thiocolchicoside is a muscle relaxant with anti-inflammatory and analgesic effects. It is commonly used to treat back pain and other pains caused by vertebral column or spinal cord disorders. Here are some key points about thiocolchicoside:

Mechanism of Action:
The exact mechanism of action of thiocolchicoside is not fully understood.
It is believed to act via antagonism of nicotinic acetylcholine receptors (nAchRs).
Additionally, it appears to be a competitive antagonist of GABA A and glycine receptors.

Medical Uses:

Low Back Pain: Thiocolchicoside is efficacious in reducing pain intensity, improving physical flexibility, and reducing muscle spasms in patients with low back pain.
When added to standard nonsteroidal anti-inflammatory drug (NSAID) therapy, it further reduces pain intensity and improves functional status.
It should not be used in seizure-prone individuals due to its powerful convulsant activity.

Safety and Precautions:
Thiocolchicoside is generally safe when taken in appropriate amounts.
Possible side effects include nausea, heartburn, diarrhea, constipation, drowsiness, skin reactions, and headaches.

Allergic reactions may occur in people with shellfish allergies. Individuals with asthma should use it cautiously.
Early research suggests that thiocolchicoside might cause the spread or recurrence of prostate cancer. Remember to consult a healthcare provider before using any medication or supplement